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Certificate of Analysis

The lab document that reports what tests were run on a batch and whether it passed - your core proof of quality.

A Certificate of Analysis (COA) is the document a lab issues summarizing the tests performed on a specific batch, the methods used, the specifications, and the pass/fail results. It's the single most important quality document you'll handle.

A real COA shows the product and lot number, each test with its actual numerical result (not just "PASS"), the method reference, the lab's accreditation details, and a signature. Generic COAs with no numbers, no letterhead, and no report number are red flags - and get rejected by Amazon and scrutinized by the FDA.

Guides that cover Certificate of Analysis

Cost & Pricing

How Much Does Supplement Testing Actually Cost?

Amazon & Marketplace

Amazon Supplement Compliance: Don't Get Delisted

FDA & GMP

The "Oh Crap, The FDA Is Calling" Guide to 21 CFR 111 Testing Requirements

Getting Started

How to Find a Supplement Testing Lab — The Complete Guide

Test Methods

Heavy Metal Testing for Supplements: Methods, Costs, and What You're Actually Testing For

Test Methods

Shelf-Life and Stability Testing: How Long Does Your Supplement Actually Last?

Manufacturing

Contract Manufacturer Testing: Why 'They Handle It' Is the Most Dangerous Phrase in Supplements

Getting Started

Supplement Testing for New Brands: What to Do First (Before You Waste Money)

Getting Started

How to Read a Certificate of Analysis: What the Numbers Actually Mean

Test Methods

Probiotic Testing: CFU Counts, Strain Verification, and Shelf-Life Stability

Specialized

CBD Testing: Potency, THC Limits, and the Tests That Keep Your Product Legal

Compliance

Importing Supplements: The Testing and Customs Documentation You Need to Clear the FDA

Manufacturing

Private Label Supplement Testing: Why Your Manufacturer's COA Isn't Enough

Manufacturing

How to Source Ingredients That Actually Pass Prop 65 Testing

Specialized

Mushroom Supplement Testing: Is It Actually Mushrooms or Just Grain Powder?

Getting Started

Your Supplement Failed Testing. Now What?

Selling Online

How to Use Your Test Results in Marketing (Without Getting an FDA Letter)

Selling Online

Amazon Supplement Reinstatement: How to Get Your Listing Back After a Compliance Removal

Test Methods

Is Your Magnesium Glycinate Actually Magnesium Oxide? How to Test What's Really in the Bottle

Getting Started

How to Test Your Supplement Before Selling (First Batch Checklist)

FDA & GMP

Supplement Finished Product Testing: The GMP Release Checklist

Getting Started

Are Your Supplier's COAs Real? How to Verify Raw Material Testing

Manufacturing

How to Switch Supplement Testing Labs Without Screwing Up Your Compliance

Getting Started

Do I Actually Need to Test My Supplements? The Honest Answer

Free Resources

Free Supplement Specification & COA Templates

Selling Online

Amazon Supplement Approved Lab List — What Labs Amazon Actually Accepts

Selling Online

How to Upload a COA to Amazon Seller Central — Step by Step

Getting Started

Supplement Lab Comparison — Eurofins vs SGS vs Intertek vs ALS vs Independent Labs

Test Methods

Allergen & Gluten-Free Testing for Supplements — ELISA Methods

Ingredient Testing

Ashwagandha Testing: Withanolides, Root Auth, Heavy Metals

Test Methods

Botanical Identity Testing — HPTLC, Microscopy, DNA Barcoding

Specialized

Collagen Supplement Testing — Amino Acid Profile Verification

Ingredient Testing

Creatine Supplement Testing: Purity, Impurities by HPLC, and Creapure Verification

Test Methods

DNA Barcoding Supplement Identity: Species Authentication by qPCR

Specialized

Electrolyte Powder Testing — Sodium, Potassium, Magnesium Verification

FDA & GMP

FDA Warning Letters for Supplements -- Testing Violations

Amazon & Marketplace

GMP Certificate for Amazon -- Do You Need One?

Specialized

Greens Powder Testing — Heavy Metals, Pesticides, Nutritional Panel

Getting Started

How to Prepare Supplement Samples for Lab Testing — Shipping, Packaging, Chain of Custody

Test Methods

HPLC Potency Testing for Supplements — How It Works

Test Methods

ICP-MS vs AAS for Supplement Heavy Metal Testing — Which Method?

Getting Started

ISO 17025 for Supplement Testing, Explained

Getting Started

ISO 17025 vs Non-Accredited Labs: Why It Matters for Supplement Testing

Ingredient Testing

L-Theanine Supplement Testing: HPLC Purity, L vs D Enantiomer Verification, and Identity

Compliance

Supplement Label Claim Substantiation — Testing Every Word on Your Bottle

Ingredient Testing

Maca Root Testing: Identity, Macamide Markers, and Heavy Metal Screening

Test Methods

Melamine Testing Supplements: Detecting Nitrogen Spiking by LC-MS/MS

Test Methods

Mycotoxin Testing Supplements: Aflatoxins, Ochratoxin A, Fumonisins

Ingredient Testing

NMN Supplement Testing: Purity by HPLC, NMN vs NR Verification, and Regulatory Status

Specialized

Omega-3 & Fish Oil Supplement Testing — EPA, DHA, TOTOX

Test Methods

PAH Testing Supplements: Polycyclic Aromatic Hydrocarbons by GC-MS

Ingredient Testing

Prenatal Vitamin Testing: Folate Form, Heavy Metal Safety, Potency

Ingredient Testing

Protein Powder Testing: Heavy Metals, Amino Spiking, and Real Protein Content

Test Methods

Residual Solvent Testing for Supplements — USP <467>

Ingredient Testing

Saw Palmetto Testing: Fatty Acid Profile, Adulteration, Identity

Ingredient Testing

Sea Moss Testing: Iodine Content, Heavy Metals, Species Auth

Compliance

Skip Lot Testing for Supplements — When You Can Reduce Testing

Compliance

Structure/Function Claims Testing Requirements

Compliance

Supplement Facts Panel Testing Requirements

Getting Started

Third-Party Supplement Testing: Why It's Non-Negotiable

Ingredient Testing

Turmeric Curcumin Testing: Potency, Lead Chromate, Identity

Ingredient Testing

Vitamin C Testing: Ascorbic Acid HPLC Potency, Degradation, Stability

Specialized

Vitamin D Potency Testing — HPLC vs LC-MS/MS Methods

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